PROCESS STRATEGIES FOR ALKALINE LIPASE PRODUCTION USING Aspergillus Niger MTCC 2594

2011-01-10 2011-01-15 2011-01-25 3/3/2025 1:13:10 AM Journal of Applied Pharmacy 3 2011 Original research article 1 8 2011 JAppPharm (2011 ). 3. 1-8 https://doi.org/10.21065/19204159.3.1 English Suraj Abraham ,2,3*; Numbi Ramudu Kamini3 and Marichetti Kuppuswami Gowthaman3 Aspergillus niger MTCC 2594, substrate inhibition, Fed batch, Production, Shake flask, Submerged stir tank fermenter] We report scale-up production of alkaline lipases from Aspergillus niger MTCC 2594 using submerged stir tank fermenter (SSTF). The batch culture experiments and biomass studies suggest that olive oil used in the process reduced enzyme yield. We found that the addition of olive oil intermittently might be a potential fed-batch strategy to improve lipase production using Aspergillus niger MTCC 2594.