EVALUATION OF ANTIEMETIC POTENTIAL OF AQUEOUS BARK EXTRACT OF CINNAMON LOUREIROI

2014-01-10 2014-01-15 2014-01-25 11/17/2024 12:20:59 PM Canadian Journal of Applied Sciences 4 2014 Original research article 26 32 2014 CanJAppSci (2014 ). 4. 26-32 http://dx.doi.org/10.21065/19257430.4.26 English Imran Ahmad Khan Antiemetic, Cinnamons loureiroi, chi-ck emesis model, Domperidone, Metoclopramide, Chlorpromazine Crude aqueous bark extract of Cinnamon loureiroi. was evaluated for anti-emetic potential. Emesis was induced by the oral administration of copper sulphate and fresh aqueous extract of Brassica compestris to male chicks of fifteen days age. The anti-emetic activity was determined by calculating the mean decrease in number of retching in contrast with those of control. Cinnamon (3 and 6 mg / kg body weight orally) showed anti-emetic activity when compared with standard drugs Chlorpromazine , Domperidone and Metoclopramide. Both the extracts, showed the antiemetic activity, highest (79.22% inhibition) and the lowest (58. 94 % inhibition) in copper sulphate induced emesis and highest (81.91% ) and the lowest( 59.57%) in Brassica compestris induced emesis.